A Common Sense Approach to Respiratory Viruses — Part 2
A practical, two-part guide on viruses and immunity—including how to support your own viral defenses.
Christof Plothe, D.O.
Part 2: Health-promoting suggestions for the common cold, influenza, RSV, coronaviruses, and more.
For part 1 of A Common Sense Approach to Respiratory Viruses, click here.
When should we start supporting our viral defenses?
Ideally, your lifestyle should be an immune-supportive one as a prophylaxis. This should include your diet, sleep, exercise, and your mental, emotional and spiritual state, as well as a reduction of EMF exposure.
When you feel the first signs of infection, you should immediately shift your diet (see below) and start with Vitamin D, NAC, Zinc, Quercetin, and Vitamin C.
The foundation of good immunity: our diet
A balanced diet supplies you with all nutrients your organism needs and nourishes your gut microbiome, which is responsible for up to 80% of our immune response. People with a balanced diet and an average daily consumption of >500 g of vegetables and fruit and >10 g of nuts had an 86% lower risk of Covid-19 compared with those whose diet was not balanced and who consumed lower amounts of these products (Jagielski, 2022). It is advisable to include the most essential categories daily.
These are:
Fermented legumes
Root vegetables
Vegetables
Greens
Nuts, seeds, flaxseeds
Fruits
Berries
Cruciferous vegetables
Sulfides (onions, garlic, leeks, etc.)
Herbs and spices
Fermented grains (sourdough, etc.) in times of prophylaxis. During an infection, you should refrain from grains.
Please note that especially during a viral infection, it is paramount to use wholefood plant-based nutrition (Alam, 2019; Ferreira, 2020; Janda, 2020; Zuo, 2021) as animal proteins increase inflammatory responses and can negatively influence your immune response (Butler, 2020; Connaughton, 2016; Greger, 2012; Zabetakis, 2020). Please also refrain from sugar and grains as they have been demonstrated to assist viral entry into the body. 240,000 studies have been evaluated for Covid-19 progression for severity and death, and sugar has been placed as the main factor responsible for it (Logette, 2021). Consumption of sugar causes chronic inflammation, harms the interferon secretion in epithelial cells, and impedes the antiviral function of natural immune cells, T cells, and B cells. Sugar also damages phagocytic cells (which swallow germs) and gut microbes.
Ways to boost the microbiome
The easiest way to boost our bacteria in the gut is to give them good food (prebiotic foods). These are fiber-rich foods (fermented wholegrains, vegetables like broccoli, brussels sprouts, root vegetables, legumes) and foods like garlic, onions, artichokes, bananas, and chicory. As our bacteria feed on different phytochemicals, you should also make your daily foods as colorful as possible, as this will increase the number of different varieties.
One easy way to support the microbiome is to eat fresh and live fermented foods like Sauerkraut or Kimchi, or learn to ferment your own at home.
Vitamin D
Please check your Vitamin D levels regardless of the season and supplementation. The ideal value should be between 50 and 80 ng/ml. Make sure you are in this range, which is significantly higher than most labs use as their reference levels, by repeating the measurement after three weeks if not achieved in the first analysis. Vitamin D has proven to be a key modulator in all three respiratory viral infections (Vaghari-Tabari, 2021). There is a well-established inverse relationship between the risk of respiratory viral pathogens, including influenza, Covid-19, and 25(OH)D levels (Gunville, 2013; Ingham, 2014; Sabetta, 2015).
Zinc and an ionophore (Quercetin) and Vitamin C
As we previously learned, an allopathic doctor is mostly helpless against a viral challenge. Since Covid times, this has changed. According to peer-reviewed studies, zinc (Sadeghsoltani, 2021) and zinc combined with an ionophore like Quercetin, inhibit the influenza virus and Covid-19. An ionophore is a molecule that can act as a facilitator and enhance zinc entry into the cell. Zinc is a decidedly anti-viral mineral. High intracellular concentrations inhibit the replication of RNA-type viruses, such as SARS-CoV-2. Quercetin is a phytochemical and, in itself, has demonstrated solid antiviral capacity (Wu 2015). Combined with Vitamin C, it develops further synergistic action (Biancatelli, 2020). Please use this combination for any viral infection as soon as possible. Vitamin C itself can help with the differentiation and proliferation of T and B cells. A lack of vitamin C will lead to impaired immunity and higher infection susceptibility.
N-acetylcysteine (NAC)
Based on a broad range of antioxidant and anti-inflammatory mechanisms, the oral administration of NAC is likely to attenuate the risk of developing Covid-19, as it was previously demonstrated for influenza and influenza-like illnesses. Administration of NAC during the winter significantly attenuated influenza and influenza-like episodes, especially in elderly high-risk individuals. NAC did not prevent A/H1N1 virus influenza infection but significantly reduced the incidence of clinically apparent disease. (De Flora, 1997). Only 25% of virus-infected subjects under NAC treatment developed a symptomatic form versus 79% in the placebo group. It also can reduce the replication of influenza viruses and reduces inflammation (Geiler, 2010).
In the event of symptoms, include the following as support:
Minimum supplementation should include:
ADULTS
Vitamin D, 10 000 IU a day
NAC, 3 x 600 mg
Quercetin, 2 x 500 mg a day, together with
Zinc, 2 x 30 mg a day
CHILDREN AND TEENAGERS, AGES 12-17
Vitamin D, 3000-5000 IU per day
Quercetin 2 x 250 mg a day, together with
Zinc, 20 mg per day, together with
Vitamin C, 1000 IU per day
NAC, 500 mg day
CHILDREN AGES 4-11 (children under 4 are in danger of choking on chewable supplements)
Vitamin D 2000-3000 IU per day
Quercetin, 250 mg a day, together with
Zinc, 20 mg per day, together with
Vitamin C 1000 IU per day
NAC, 500 mg per day
What we should know about sleep and viral infections
Sleep and circadian rhythm disruption can actually predispose you to a viral infection like Covid-19 and causes the suppression of both innate and adaptive immune systems; it should thus not be underestimated (Taylor, 2023). During sleep, the body releases essential hormones (growth hormone and melatonin), and melatonin enhances both innate and cellular immunity (Srinivasan, 2005).
So don´t watch your favorite movies late at night when infected, and better think about good sleep.
Nature and viral infections
Spending time in nature can help relieve stress and anxiety, improve your mood, and boost happiness and well-being (Bratman, 2015; Capaldi, 2014; Mayer, 2009). Nowadays, called forest bathing, ecotherapy, mindfulness in nature, green time, or the wilderness cure, humans evolved in the great outdoors, and our brains benefit from a journey back to nature. A walk in the woods also strongly activates Natural Killer (NK) cells, improving our immunity (Morimoto, 2007; Li, 2010).
So make sure to spend time outdoors, especially in nature, like in the woods or near water, if you can.
How exercise can help our immune system
Researchers who studied the preventative aspect of exercise in viral infections like Covid-19 recommend efforts to promote physical activity be prioritized by public health agencies and incorporated into routine medical care (Després, 2021).
You should not engage in vigorous exercise during and in the days after a viral infection.
How can our mental and emotional state influence our viral responses?
Stressful conditions decrease the Natural Killer cell capacity, and psychological stress thus impairs the immune system's ability to produce antibodies, thereby making the organism more vulnerable to infections (Dragos, 2010). Anything to decrease stress and mental overload will help our immune system. Make sure you are surrounded by positive mental and emotional inputs during an infection; turn off your radio, TV, Internet, and social media and enjoy nature's sounds, silence, or listen to your favorite music or an uplifting or funny audiobook.
Meditation techniques like mindfulness have been shown to affect specific markers of inflammation and cell-mediated immunity (Black, 2016). Research shows us that laughter boosts our immune system's ability to fight infection. The associated dopamine production promotes the action of Natural Killer cells. Positive thoughts also release neuropeptides that can improve overall immunity. In the last years, the effect of our emotional well-being on our defense system has been well observed. More and more scientists mention including psychology as an integral part of infection treatment strategy (Wang, 2021).
Drink enough to assist your immune system
Drink enough water to balance your fluid loss. Hydration is a crucial element in maintaining a healthy immune system. Most of us are out of our everyday routines during this Covid-19 pandemic, so it is important to remember to hydrate properly. A large part of the cells in our body are made up of water. So water plays a very important role in the functioning of every system, including the immune system. Water helps your body eliminate particular wastes that can otherwise stress our immune system. Adequate hydration means your immune system is more robust for other challenges.
It's essential to drink at least 8-10 glasses of water a day to keep your hydration levels up.
Avoid EMF exposure during infection
An ever-increasing number of studies have clearly shown various biological and medical effects at the cellular level due to electromagnetic fields. EMF radiation is classified as an immunosuppressant, which means it makes your immune system unable to respond—sometimes at all—to a pathogen like a virus. It has been demonstrated that high-frequency EMFs reduce cytotoxic activity in the peripheral blood. Many immune cell concentrations, like NK cells, were significantly altered (Boscol, 2001; Dmoch, 1998). Another level of harmful modulation of the immune system is the increase in an inflammation-promoting factor (cytokine) named IL 6 (Aghajari, 2021; Megha, 2015). EMF has been shown to elevate this while it increases inflammation.
Unfortunately, IL 6 is one of the primary progression markers of Covid-19 (Herold, 2020). So turn off your wireless devices during infection and stick to cable bound communication instead.
Author perspective
While the efficiency of all measures (Diet, supplements, etc.) has been demonstrated in numerous peer-reviewed studies, our health ministries and regulatory bodies are not telling us about it. Indeed, in countries such as New Zealand and the USA, there are moves to restrict the availability of nutraceuticals such as herbs and supplements. For example, NAC has been a widely-used dietary supplement for six decades, yet the FDA suddenly decided to crack down on it in late July 2020 — right after discovering how useful it was for preventing and treating Covid-19. As it was too effective, the new regulations declared it a drug. New proposed legislation by the FDA, if passed, will technically ban most supplements, as few supplement makers have the financial resources required to meet drug approval requirements. In Europe, the regulatory bodies have just passed similar legislation for Artemisia and Curcumin.
The main official argument for this is safety. But nutritional supplements are 62,000 times safer than pharmaceutical drugs. Yet nobody seems to be interested in banning them. Meanwhile, in the real world, not a single death has ever been reported as a direct result of taking a supplement. Make up your own mind.
References
Aghajari S, Mortazavi SMJ, Kalani M, Nematolahi S, Habibzadeh P, Farjadian S. The Immunomodulatory Effect of Radiofrequency Electromagnetic Field on Serum Cytokine Levels in A Mouse Model of Hindlimb Unloading. Cell J. 2021 Jan;22(4):401-405. doi: 10.22074/cellj.2021.6856. Epub 2020 Apr 22. PMID: 32347032; PMCID: PMC7211291.
Alam I., Almajwal A.M., Alam W., Alam I., Ullah N., Abulmeaaty M., Razak S., Khan S., Pawelec G., Paracha P.I. The immune-nutrition interplay in aging— Facts and controversies. Nutr. Heal. Aging. 2019;5:73–95. doi: 10.3233/NHA- 170034
Alexander Paul, https://brownstone.org/articles/research-studies-affirm-naturally-acquired-immunity/
Anderson ML, Dobkin C, Gorry D. The Effect of Influenza Vaccination for the Elderly on Hospitalization and Mortality: An Observational Study With a Regression Discontinuity Design. Ann Intern Med. 2020 Apr 7;172(7):445-452. doi: 10.7326/M19-3075. Epub 2020 Mar 3. PMID: 32120383.
Biancatelli R, Berrill M, Catravas, . Marik P; Front. Immunol., 19 June 2020, Sec. Viral Immunology , Volume 11 - 2020 | https://doi.org/10.3389/fimmu.2020.01451
Black DS, Slavich GM. Mindfulness meditation and the immune system: a systematic review of randomized controlled trials. Ann N Y Acad Sci. 2016 Jun;1373(1):13-24. doi: 10.1111/nyas.12998. Epub 2016 Jan 21. PMID: 26799456; PMCID: PMC4940234.
Bogdándi EN, Balogh A, Felgyinszki N, Szatmári T, Persa E, Hildebrandt G, Sáfrány G, Lumniczky K. Effects of low-dose radiation on the immune system of mice after total-body irradiation. Radiat Res. 2010 Oct;174(4):480-9. doi: 10.1667/RR2160.1. PMID: 20726712.
Boscol P, M.B. Di Sciascio, S. D’Ostilio, A. Del Signore, M. Reale, P. Conti, P. Bavazzano, R. Paganelli, M. Di Gioacchino, Effects of elec- tromagnetic fields produced by radiotelevision broadcasting stations on the immune system of women, Sci. Total Environ. 273 (2001) 1–10.
Bratman GN, Hamilton JP, Hahn KS, et al. Nature experience reduces rumination and subgenual prefrontal cortex activation. Proceedings of the National Academy of Sciences of the United States of America. 2015(112);28:8567-8572. doi: 10.1073/pnas.1510459112.
Butler MJ, Barrientos RM. The impact of nutrition on COVID-19 susceptibility and long-term consequences. Brain Behav Immun. 2020;87:53-54. doi:10.1016/j.bbi.2020.04.040
Capaldi C, Dopko RL, Zelenski J. The relationship between nature connectedness and happiness: a meta-analysis. Frontiers in Psychology. 2014. doi: 10.3389/fpsyg.2014.00976.
Connaughton R.M., McMorrow A.M., McGillicuddy F.C., Lithander F.E., Roche H.M. Impact of anti- inflammatory nutrients on obesity-associated metabolic- inflammation from childhood through to adulthood. Proc. Nutr. Soc. 2016;75:115–124. doi: 10.1017/S0029665116000070
De Flora S, Grassi C, Carati L. Attenuation of influenza-like symptomatology and improvement of cell-mediated immunity with long-term N-acetylcysteine treatment. Eur Respir J. 1997 Jul;10(7):1535-41. doi: 10.1183/09031936.97.10071535. PMID: 9230243.
Després, JP. Severe COVID-19 outcomes — the role of physical activity. Nat Rev Endocrinol 17, 451–452 (2021). https://doi.org/10.1038/s41574-021-00521-1
Dmoch A, P. Moszczynski, Levels of immunoglobulin and subpopu- lations of T lymphocytes and NK cells in men occupationally exposed to microwave radiation in frequencies of 6–12 GHz [Article in Polish], Med. Pr. 49 (1998) 45–49.
Dragoş D, Tănăsescu MD. The effect of stress on the defense systems. J Med Life. 2010 Jan-Mar;3(1):10-8. PMID: 20302192; PMCID: PMC3019042.
FDA, 2020; https://www.fda.gov/food/dietary-supplements/whats-new-dietary-supplements
Ferreira, C.; Viana, S.D.; Reis, F. Gut Microbiota Dysbiosis–Immune Hyperresponse– Inflammation Triad in Coronavirus Disease 2019 (COVID- 19): Impact of Pharmacological and Nutraceutical Approaches. Microorganisms 2020, 8, 1514.
FLCC, 2023; https://covid19criticalcare.com/wp-content/uploads/2022/12/I-CARE-RSV-AND-FLU-TREATMENT-Summary.pdf
Geiler J, Michaelis M, Naczk P, Leutz A, Langer K, Doerr HW, Cinatl J Jr. N-acetyl-L-cysteine (NAC) inhibits virus replication and expression of pro-inflammatory molecules in A549 cells infected with highly pathogenic H5N1 influenza A virus. Biochem Pharmacol. 2010 Feb 1;79(3)
Greger, 2012; https://nutritionfacts.org/2012/09/20/why-meat-causes- inflammation/
Herold T, Jurinovic V, Arnreich C, Lipworth BJ, Hellmuth JC, von Bergwelt-Baildon M, Klein M, Weinberger T. Elevated levels of IL-6 and CRP predict the need for mechanical ventilation in COVID-19. J Allergy Clin Immunol. 2020 Jul;146(1):128-136.e4. doi: 10.1016/j.jaci.2020.05.008. Epub 2020 May 18. PMID: 32425269; PMCID: PMC7233239.
Jagielski P, Łuszczki E, Wnęk D, Micek A, Bolesławska I, Piórecka B, Kawalec P. Associations of Nutritional Behavior and Gut Microbiota with the Risk of COVID-19 in Healthy Young Adults in Poland. Nutrients. 2022 Jan 14;14(2):350. doi: 10.3390/nu14020350. PMID: 35057534; PMCID: PMC8779092.
Janda, L., Mihalčin, M. & Šťastná, M. Is a healthy microbiome responsible for lower mortality in COVID-19?. Biologia (2020). https://doi.org/10.2478/s11756-020-00614-8
Johansson O. Disturbance of the immune system by electromagnetic fields-A potentially underlying cause for cellular damage and tissue repair reduction which could lead to disease and impairment. Pathophysiology. 2009 Aug;16(2-3):157-77. doi: 10.1016/j.pathophys.2009.03.004. Epub 2009 Apr 23. PMID: 19398310.
Lauck, 2015; https://journals.asm.org/doi/10.1128/jvi.02752-14
Li Q. Effect of forest bathing trips on human immune function. Environ Health Prev Med. 2010 Jan;15(1):9-17. doi: 10.1007/s12199-008-0068-3. PMID: 19568839; PMCID: PMC2793341.
Logette E, Lorin C, Favreau C, Oshurko E, Coggan JS, Casalegno F, Sy MF, Monney C, Bertschy M, Delattre E, Fonta PA, Krepl J, Schmidt S, Keller D, Kerrien S, Scantamburlo E, Kaufmann AK, Markram H. A Machine-Generated View of the Role of Blood Glucose Levels in the Severity of COVID-19. Front Public Health. 2021 Jul 28;9:695139. doi: 10.3389/fpubh.2021.695139. PMID: 34395368; PMCID: PMC8356061.
Mayer F, Frantz C, Bruehlman-Senecal E, Dolliver K. Why Is Nature Beneficial? The Role of Connectedness to Nature. 2009;41:607-643. Doi: 10.1177/0013916508319745
Megha K, Deshmukh PS, Banerjee BD, Tripathi AK, Ahmed R, Abegaonkar MP. Low intensity microwave radiation induced oxidative stress, inflammatory response and DNA damage in rat brain. Neurotoxicology. 2015 Dec;51:158-65. doi: 10.1016/j.neuro.2015.10.009. Epub 2015 Oct 25. PMID: 26511840.
Morimoto L, Nakadai A, Inagaki H, Katsumata M, Shimizu T, Hirata Y, Hirata K, Suzuki H, Miyazaki Y, Kagawa T, Koyama Y, Ohira T, Takayama N, Krensky AM, Kawada T. Forest bathing enhances human natural killer activity and expression of anti-cancer proteins. Int J Immunopathol Pharmacol. 2007 Apr-Jun;20(2 Suppl 2):3-8. doi: 10.1177/03946320070200S202. PMID: 17903349.
NZ, 2023; https://www.parliament.nz/en/pb/sc/make-a-submission/document/53SCHE_SCF_BILL_130084/therapeutic-products-bill?fbclid=IwAR3cy_puuIivEeNg2Pq2tZoVlJmPUz8pso4m8SKff9oJnS8uMhow7-sOOCk
Pasteur Institute Press Release – Towards new vaccination strategies based on ‘non specific immunity’; August 1, 2000.
Schwarze-Zander C, Blackard JT, Rockstroh JK. Role of GB virus C in modulating HIV disease. Expert Rev Anti Infect Ther. 2012 May;10(5):563-72. doi: 10.1586/eri.12.37. PMID: 22702320; PMCID: PMC3499065.
Srinivasan V, Maestroni GJ, Cardinali DP, Esquifino AI, Perumal SR, Miller SC. Melatonin, immune function and aging. Immun Ageing. 2005 Nov 29;2:17. doi: 10.1186/1742-4933-2-17. PMID: 16316470; PMCID: PMC1325257.
Taylor L, Von Lendenfeld F, Ashton A, Sanghani H, Di Pretoro S, Usselmann L, Veretennikova M, Dallmann R, McKeating JA, Vasudevan S, Jagannath A. Sleep and circadian rhythm disruption alters the lung transcriptome to predispose to viral infection. iScience. 2022 Dec 24;26(2):105877. doi: 10.1016/j.isci.2022.105877. Epub ahead of print. PMID: 36590897; PMCID: PMC9788990.
Vaghari-Tabari M, Mohammadzadeh I, Qujeq D, Majidinia M, Alemi F, Younesi S, Mahmoodpoor A, Maleki M, Yousefi B, Asemi Z. Vitamin D in respiratory viral infections: a key immune modulator? Crit Rev Food Sci Nutr. 2021 Sep 2:1-16. doi: 10.1080/10408398.2021.1972407. Epub ahead of print. PMID: 34470511.
Wang SC, Su KP, Pariante CM. The three frontlines against COVID-19: Brain, Behavior, and Immunity. Brain Behav Immun. 2021 Mar;93:409-414. doi: 10.1016/j.bbi.2021.01.030. Epub 2021 Feb 4. PMID: 33548496; PMCID: PMC7857976.
Wu W, Li R, Li X, He J, Jiang S, Liu S, Yang J. Quercetin as an Antiviral Agent Inhibits Influenza A Virus (IAV) Entry. Viruses. 2015 Dec 25;8(1):6. doi: 10.3390/v8010006. PMID: 26712783; PMCID: PMC4728566.
Zabetakis I, Lordan R, Norton C, Tsoupras A. COVID-19: The Inflammation Link and the Role of Nutrition in Potential Mitigation. Nutrients. 2020;12(5):1466. Published 2020 May 19. doi:10.3390/nu12051466
Zuo T, Liu Q, Zhang F, et al Depicting SARS-CoV-2 faecal viral activity in association with gut microbiota composition in patients with COVID-19 Gut 2021;70:276-284.
Disclaimer: The views expressed in this submission are Christof’s own and do not necessarily represent the World Council for Health.
Please help support our work!
If you have the means, please consider supporting the World Council for Health.
You can either pledge a subscription on Substack, or give directly to WCH.
Can’t donate but would like to contribute? We’re always looking for volunteers, so please do get in touch!
Melatonin is not only a sleep aid but a powerful antioxydant. It supports the immune system and more. 1, 2 or 3mg before go to sleep. Just a suggestion.
Thank you, but there is no evidence that viruses actually exist. My recent article shares a succinct lecture of explanation.